Platelet-Rich Plasma (PRP) is the process of preparing platelets and human growth factors from a blood sample into an injectable plasma solution. The result, a “PRP serum”, is activated to release essential growth factors in their natural and biologically-determined ratios, along with their signalling proteins.
Over 20 years ago, PRP was used in the dental field for promoting accelerated wound healing in cancer patients following jaw reconstruction. Physicians have used PRP to aid bone healing after spinal injury and soft tissue recovery following plastic surgery. Recently, PRP has gained an almost cult-like status due to its impressive results and popularity with celebrities like Kim Kardashian and Bar Refaeli.
Blood is obtained by the process of venesection, similar to a routine blood test. This is stored in a sterile syringe to prevent infection and contamination. A process of centrifugation is then undertaken which involves a machine spinning down blood into its constituent parts. The plasma-rich layer is then extracted and injected back into the same patient under sterile conditions. We use medical grade numbing cream to minimise any discomfort. Injected into the skin, this plasma releases proteins which stimulate collagen and elastin growth, increasing elasticity whilst adding a natural fullness and healthy, youthful look. Over the days and weeks following the Cellenis® PRP treatment, growth factors released by the platelets stimulate the growth of new blood vessels and more collagen growth, thickening the epidermis and providing an improvement in the skin’s texture and tone.
PRP contains the primary cells the body needs to heal injuries and regenerate tissue, including:
- Vascular Endothelial Growth Factors: Responsible for the growth of the cells that line the inner surface of blood vessels.
- Epidermal Growth Factors: Key for skin cell regeneration.
- Transforming Growth Factors: Stimulate the creation of normal cells.
- Fibroblast Growth Factors: Assist with collagen creation which adds structure beneath the skin.
- Hepatocyte Growth Factors: Used to repair of the cells of the liver.
- Insulin-like Growth Factors: Used to grow and repair tissue and bones.
- Critical thrombocytopenia (low platelet count)
- Haemodynamic instability (collapse)
- Sepsis (infection)
- Acute and chronic infections
- Chronic liver disease
- Anti-coagulation therapy (warfarin, dabigatran, heparin).